Looking Healthy is Part of the Job

We must work hard Eating right, maintaining our Health with Dental care,
Skin care, Weight maintenance and Annual Checkups. We must also seek
a Moral Compass and get a Serious Relationship with our Creator. For phy-
sical  & Spiritual Well Being!

Are perms responsible for Uterine Fibroids?

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/perms-linked-to-uterine-fibroid-tumors-and-early-puberty,
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Hair Relaxer Use and Risk of Uterine Leiomyomata in African-American Women

1. Lauren A. Wise*, 
2. Julie R. Palmer, 
3. David Reich, 
4. Yvette C. Cozier and 
5. Lynn Rosenberg

1. ↵*Correspondence to Dr. Lauren A. Wise, Slone Epidemiology Center, Boston University, 1010 Commonwealth Avenue, Boston, MA 02215 (e-mail: lwise@bu.edu).

• Received June 15, 2011.
• Accepted September 9, 2011.

Abstract

Hair relaxers are used by millions of black women, possibly exposing them to various chemicals through scalp lesions and burns. In the Black Women’s Health Study, the authors assessed hair relaxer use in relation to uterine leiomyomata incidence. In 1997, participants reported on hair relaxer use (age at first use, frequency, duration, number of burns, and type of formulation). From 1997 to 2009, 23,580 premenopausal women were followed for incident uterine leiomyomata. Multivariable Cox regression was used to estimate incidence rate ratios and 95% confidence intervals. 

During 199,991 person-years, 7,146 cases of uterine leiomyomata were reported as confirmed by ultrasound (n = 4,630) or surgery (n = 2,516). The incidence rate ratio comparing ever with never use of relaxers was 1.17 (95% confidence interval (CI): 1.06, 1.30). Positive trends were observed for frequency of use (P_trend< 0.001), duration of use (P_trend = 0.015), and number of burns (P_trend < 0.001). 

Among long-term users (≥10 years), the incidence rate ratios for frequency of use categories 3–4, 5–6, and ≥7 versus 1–2 times/year were 1.04 (95% CI: 0.92, 1.19), 1.12 (95% CI: 0.99, 1.27), and 1.15 (95% CI: 1.01, 1.31), respectively (P_trend = 0.002). Risk was unrelated to age at first use or type of formulation. These findings raise the hypothesis that hair relaxer use increases uterine leiomyomata risk.